Effect of Pomegranate Peel Extract Alternatives to Oxytetracycline on Growth Peformance and Physiological Homeostasis in Rabbits

The current study focused on evaluation of pomegranate peel extract (PPE) and the oxytetracycline as antioxidant antiapoptotic potentialities New Zealand White rabbits (NZW) performance, physiological homeostasis, hemato-biochemical indices stabilized DNA structure resembling in 8-hydroxy-2-deoxyguanosine (8OH2dG) level. For this purpose, four groups (each one compromise 6 animals) weaned NZW aged weeks were randomly divided follows: 1st group preserved normal control (C) treated with tap water; 2nd (OXY) daily oral dose Oxytetracycline 200 mg/kg BW/day; 3rdgroup 130 BW/day PPE; 4th OXY + PPE 100 65 PPE. experiment lasted for 8 weeks. Concerning growth parameters, results showed that treatment its combination enhanced body weight ameliorate negative effect liver kidney function minimal side effects. In addition elevate parameters. However, decreases parameters (live gain), total protein, albumin, globulin A/G ratio levels induces markedly increases AST, ALT, creatinine, cortisol, 8OH2dG concentrations. conclusion, present aimed to investigate common effects when compared natural suggests at half each oxytetracycline, accelerate normalize homeostasis.